Hydrogen Sulfide: Redox Metabolism and Signaling
- 15 July 2011
- journal article
- editorial
- Published by Mary Ann Liebert Inc in Antioxidants and Redox Signaling
- Vol. 15 (2), 339-341
- https://doi.org/10.1089/ars.2011.3912
Abstract
The recognition of hydrogen sulfide (H2S) as an endogenously produced gas with signaling potential has stimulated research on a multitude of physiological effects mediated in the cardiovascular, immune, gastrointestinal, genitourinary, endocrine, and central nervous systems. The heightened activity in the area of H2S biology led to convening of the first international conference on H2S in Shanghai in the summer of 2009 and to two Forum issues published in 2010 by Antioxidants & Redox Signaling on the physiological effects of H2S. Yet, fundamental questions regarding the biogenesis and regulation of H2S, the bioenergetics of its catabolism, its tissue concentrations, and elucidation of its molecular targets remain. Some of these issues are the subject of the current Forum on H2S. Antioxid. Redox Signal. 15, 339–341.Keywords
This publication has 32 references indexed in Scilit:
- The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine TissuesAntioxidants and Redox Signaling, 2011
- Hydrogen Sulfide and Hemeproteins: Knowledge and MysteriesAntioxidants and Redox Signaling, 2011
- Inhaled Hydrogen Sulfide Prevents Neurodegeneration and Movement Disorder in a Mouse Model of Parkinson's DiseaseAntioxidants and Redox Signaling, 2011
- Cystathionine γ-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative InjuryOnline Journal of Public Health Informatics, 2010
- Redox Biochemistry of Hydrogen SulfideOnline Journal of Public Health Informatics, 2010
- Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration ReactionsOnline Journal of Public Health Informatics, 2009
- H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of HyperhomocysteinemiaJournal of Biological Chemistry, 2009
- H 2 S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-LyaseScience, 2008
- Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial functionProceedings of the National Academy of Sciences of the United States of America, 2007
- The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel openerThe EMBO Journal, 2001