Chlamydia trachomatisProctitis
- 23 July 1981
- journal article
- case report
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 305 (4), 195-200
- https://doi.org/10.1056/nejm198107233050404
Abstract
One hundred seventy-one homosexual men, 96 of whom had symptoms suggestive of proctitis and 75 of whom had no such symptoms, were consecutively enrolled in a study of the prevalence, clinical spectrum, and histopathology of Chlamydia trachomatis rectal infections. C. trachomatis was isolated from the rectums of 14 men. Three of the isolates, which had lymphogranuloma venereum (LGV) immunotypes, were recovered from three men with symptoms and signs of severe proctitis, two of whom had granulomatous inflammation that was observed at rectal biopsy and was initially suggestive of Crohn's disease. Eleven isolates, which had non-LGV immunotypes, were obtained from eight symptomatic and three asymptomatic men, all of whom had fecal leukocytes and mild abnormalities of the mucosa present at sigmoidoscopy, usually with mild nongranulomatous inflammatory changes that were seen on rectal biopsy. These observations suggest that the presence of LGV immunotypes of C. trachomatis in the rectum is associated with severe acute proctitis that mimics Crohn's disease of the rectum, whereas the non-LGV immunotypes are associated with a mild proctitis with or without symptoms. (N Engl J Med. 1981; 305: 195–200.)Keywords
This publication has 26 references indexed in Scilit:
- Confirmatory Serodiagnosis of Lymphogranuloma Venereum Proctitis May Yield False- Positive Results Due to Other Chlamydia1 Infections of the RectumSexually Transmitted Diseases, 1981
- CHLAMYDIA, CYTOMEGALOVIRUS, AND YERSINIA IN INFLAMMATORY BOWEL DISEASEThe Lancet, 1979
- LOW FREQUENCY OF CHLAMYDIAL ANTIBODIES IN PATIENTS WITH CROHN'S DISEASE AND ULCERATIVE COLITISThe Lancet, 1979
- ANTIBODIES AGAINST CHLAMYDIA OF LYMPHOGRANULOMA-VENEREUM TYPE IN CROHN'S DISEASEThe Lancet, 1979
- Antibiotic-Associated Pseudomembranous Colitis Due to Toxin-Producing ClostridiaNew England Journal of Medicine, 1978
- Chlamydial InfectionsNew England Journal of Medicine, 1978
- Crohn's disease of the anal region.Gut, 1965
- Lymphogranuloma venereumDiseases of the Colon & Rectum, 1964
- Positive Frei Tests in 7 Cases of Morbus Crohn (Regional Ileitis)Digestion, 1963
- Rectal lymphogranuloma venereumBritish Journal of Surgery, 1957