Universal Access to Effective Antibiotics is Essential for Tackling Antibiotic Resistance
- 1 January 2015
- journal article
- research article
- Published by Cambridge University Press (CUP) in The Journal of Law, Medicine & Ethics
- Vol. 43 (S3), 17-21
- https://doi.org/10.1111/jlme.12269
Abstract
Universal access to effective antimicrobials is essential to the realization of the right to health. At present, 5.7 million people die from treatable infections each year because they lack this access. Yet, community-based diagnosis and appropriate treatment for many of the leading causes of avoidable infectious deaths has been shown to be feasible and effective, demonstrating that strategies to reach the under-served need to receive high priority. This is a necessary part of a broad strategy to assure the long-term benefits of antimicrobials and to combat antimicrobial resistance, both because the lack of systematic and rigorous efforts to assure effective coverage increases the likelihood of antimicrobial resistance, and because global efforts aimed at antimicrobial stewardship and innovation cannot succeed without explicitly addressing the needs of the under-served. Elements of this strategy will include clear evidence-based treatment protocols, a robust international framework and locally tailored regulations, active engagement with communities and local health providers, strong attention to program management and cost considerations, a focus on the end user, and robust surveillance and response to emerging resistance patterns. Only by balancing the needs of universal access with stewardship and innovation, and assuring that they are mutually reinforcing can a global strategy hope to effectively address antimicrobial resistance.Keywords
This publication has 16 references indexed in Scilit:
- Antibiotic Resistance — Problems, Progress, and ProspectsThe New England Journal of Medicine, 2014
- The need to look at antibiotic resistance from a health systems perspectiveUpsala Journal of Medical Sciences, 2014
- Which doctor for primary health care? Quality of care and non-physician clinicians in IndiaSocial Science & Medicine (1982), 2013
- The Lancet–University of Oslo Commission on Global Governance for Health, in collaboration with the Harvard Global Health InstituteThe Lancet, 2011
- Recommendations for treatment of childhood non-severe pneumoniaThe Lancet Infectious Diseases, 2009
- Home-based management of fever and malaria treatment practices in UgandaTransactions of the Royal Society of Tropical Medicine and Hygiene, 2007
- Antimicrobial resistance in developing countries. Part I: recent trends and current statusThe Lancet Infectious Diseases, 2005
- Hospital-acquired neonatal infections in developing countriesThe Lancet, 2005
- Reduction in total under-five mortality in western Nepal through community-based antimicrobial treatment of pneumoniaThe Lancet, 1991
- A Half Century of Neonatal Sepsis at YaleAmerican Journal of Diseases of Children, 1981