Supplementary Figures 1-4 from A High-Throughput Functional Complementation Assay for Classification of BRCA1 Missense Variants

Abstract

Supplementary Figures 1-4 - PDF 213K, This file contains additional data on the generation of R26CreERT2/RMCE;Brca1SCo/{delta} ES cells and analysis of Rosa26 targeted human BRCA1 cDNA expression (Fig. S1), analysis of BRCA1 VUS protein and mRNA expression (Fig. S2 and S3) and growth curves supplementary to Figure 6 (Fig. S4)