The SV40 early region TATA box is required for accurate in vitro initiation of transcription
- 1 March 1981
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 290 (5804), 310-315
- https://doi.org/10.1038/290310a0
Abstract
The SV40 early region TATA box functions in vitro to fix initiation of transcription within a narrow region identical to that in vivo. In the absence of the TATA box region initiation occurs at multiple specific sites, as in vivo. However, certain sequences far upstream, crucial for efficient in vivo expression, are not essential in vitro.Keywords
This publication has 27 references indexed in Scilit:
- Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence.Proceedings of the National Academy of Sciences of the United States of America, 1980
- Promoter Sequences of Eukaryotic Protein-Coding GenesScience, 1980
- Accurate transcription initiation on a purified mouse β-globin DNA fragment in a cell-free systemCell, 1980
- DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.Proceedings of the National Academy of Sciences, 1980
- The transcription of eukaryotic genesNature, 1980
- Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genesNature, 1980
- Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.Proceedings of the National Academy of Sciences, 1980
- Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dnaCell, 1979
- Eukaryotic promoters?Nature, 1979
- Organisation and sequences at the 5′ end of a cloned complete ovalbumin geneNature, 1979