Noninvasive temperature mapping with MRI using chemical shift water‐fat separation
Open Access
- 23 April 2010
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 63 (5), 1238-1246
- https://doi.org/10.1002/mrm.22310
Abstract
Tissues containing both water and lipids, e.g., breast, confound standard MR proton reference frequency‐shift methods for mapping temperatures due to the lack of temperature‐induced frequency shift in lipid protons. Generalized Dixon chemical shift–based water‐fat separation methods, such as GE's iterative decomposition of water and fat with echo asymmetry and least‐squares estimation method, can result in complex water and fat images. Once separated, the phase change over time of the water signal can be used to map temperature. Phase change of the lipid signal can be used to correct for non‐temperature‐dependent phase changes, such as amplitude of static field drift. In this work, an image acquisition and postprocessing method, called water and fat thermal MRI, is demonstrated in phantoms containing 30:70, 50:50, and 70:30 water‐to‐fat by volume. Noninvasive heating was applied in an Off1‐On‐Off2 pattern over 50 min, using a miniannular phased radiofrequency array. Temperature changes were referenced to the first image acquisition. Four fiber optic temperature probes were placed inside the phantoms for temperature comparison. Region of interest (ROI) temperature values colocated with the probes showed excellent agreement (global mean ± standard deviation: −0.09 ± 0.34°C) despite significant amplitude of static field drift during the experiments. Magn Reson Med 63:1238–1246, 2010.Keywords
This publication has 36 references indexed in Scilit:
- Multiecho water‐fat separation and simultaneous R estimation with multifrequency fat spectrum modelingMagnetic Resonance in Medicine, 2008
- Comparative MR study of hepatic fat quantification using single‐voxel proton spectroscopy, two‐point dixon and three‐point IDEALMagnetic Resonance in Medicine, 2008
- Relaxation effects in the quantification of fat using gradient echo imagingMagnetic Resonance Imaging, 2008
- MR thermometryJournal of Magnetic Resonance Imaging, 2008
- Water–fat separation with IDEAL gradient‐echo imagingJournal of Magnetic Resonance Imaging, 2007
- Anthropomorphic breast phantoms for testing elastography systemsJapanese Journal of Clinical Oncology, 2006
- Iterative decomposition of water and fat with echo asymmetry and least‐squares estimation (IDEAL): Application with fast spin‐echo imagingMagnetic Resonance in Medicine, 2005
- Thermal Dose Is Related to Duration of Local Control in Canine Sarcomas Treated with ThermoradiotherapyClinical Cancer Research, 2005
- Thermochemoradiotherapy Improves Oxygenation in Locally Advanced Breast CancerClinical Cancer Research, 2004
- A precise and fast temperature mapping using water proton chemical shiftMagnetic Resonance in Medicine, 1995