CRISPR/Cas: a potential gene-editing tool in the nervous system
Open Access
- 6 August 2020
- journal article
- review article
- Published by Springer Science and Business Media LLC in Cell Regeneration
- Vol. 9 (1), 1-8
- https://doi.org/10.1186/s13619-020-00044-6
Abstract
The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of use, low cost and high efficiency of CRISPR/Cas make it commonly used in various conditions. In this review, we introduce the CRISPR/Cas system and its diverse applications in nervous system briefly, which provides a better understanding for its potential application values.Keywords
Funding Information
- China National Funds for Distinguished Young Scientists (31925016)
- Major Research Plan (91957122)
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