Frequencies of X-ray-induced Chromosome Translocations in Human Peripheral Lymphocytes as Detected byin SituHybridization Using Chromosome-specific DNA Libraries
- 1 January 1992
- journal article
- research article
- Published by Informa UK Limited in International Journal of Radiation Biology
- Vol. 61 (2), 199-203
- https://doi.org/10.1080/09553009214550821
Abstract
In situ hybridization with chromosome-specific DNA libraries was used to analyse radiation-induced stable translocations in human peripheral blood lymphocytes. These data were compared with radiation-induced unstable-type aberrations (dicentrics) in the same samples. The results indicate that far more stable aberrations are induced by radiation in comparison to unstable aberrations.Keywords
This publication has 8 references indexed in Scilit:
- A cytogenetic follow-up study of the victims of a radiation accident in Goiania (Brazil)Mutation Research, 1991
- Rapid metaphase and interphase detection of radiation‐induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridizationCytometry, 1990
- Chromosomal aberration and sister-chromatid exchange frequencies in peripheral blood lymphocytes of a large human population sample II. Extension of age rangeMutation Research, 1989
- Rapid Human Chromosome Aberration Analysis Using Fluorescencein SituHybridizationInternational Journal of Radiation Biology, 1989
- Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA librariesHuman Genetics, 1988
- Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.Proceedings of the National Academy of Sciences, 1986
- The incidence of unstable chromosome aberrations in peripheral blood lymphocytes from unirradiated and occupationally exposed peopleMutation Research, 1980
- DNA Content and DNA-Based Centromeric Index of the 24 Human ChromosomesScience, 1973