Persistence Patterns of Porphyromonas gingivalis, Prevotella intermedia/ nigrescens, and Actinobacillus actinomycetemcomitans After Mechanical Therapy of Periodontal Disease
- 1 January 2000
- journal article
- Published by Wiley in The Journal of Periodontology
- Vol. 71 (1), 14-21
- https://doi.org/10.1902/jop.2000.71.1.14
Abstract
The aim of this study was to determine the distribution patterns of Porphyromonas gingivalis, Prevotella intermedia/nigrescens, and Actinobacillus actinomycetemcomitans in periodontitis patients after standard mechanical periodontal therapy, and to determine factors increasing the odds to detect these target organisms in treated sites. Eight hundred fifty-two (852) separate subgingival microbial samples were taken from the mesial and distal aspects of every tooth in 17 patients. Target organisms were identified culturally. The 3 microorganisms showed different persistence patterns: P. gingivalis was detected in a high percentage of subjects (59%), but in a low proportion of sites (5.4%). P. intermedia/nigrescens was detected in all subjects except one, and in 40.6% of the tested sites. Only 5 subjects were A. actinomycetemcomitans positive, but 2 of them showed a very high number of positive sites (44% and 75%, respectively). A highly significant relationship was found between a subject's tendency to bleed upon sampling and the number of P. intermedia/nigrescens-positive sites. A significant portion of the variation in frequency of persisting P. gingivalis could be explained by the frequency of persisting pockets deeper than 4 mm. No similar relationship could be established between clinical parameters and A. actinomycetemcomitans. On a site level, the odds of detecting P. gingivalis increased by a factor of 2.47 (P= 0.0001) for every millimeter of residual probing depth; the odds of detecting P. intermedia/nigrescens increased by a factor of 1.84 (P= 0.0001). If, after standard mechanical periodontal therapy, a large number of sites continue to bleed, one may expect an increased number of sites positive for P. intermedia/ nigrescens. If many deep pockets persist, a greater number of P. gingivalis-positive sites can be expected.Keywords
This publication has 19 references indexed in Scilit:
- Utility of 5 major putative periodontal pathogens and selected clinical parameters to predict periodontal breakdown in patients on maintenance careJournal of Clinical Periodontology, 1996
- Microbial identification and antibiotic sensitivity testing, an aid for patients refractory to periodontal therapyJournal of Clinical Periodontology, 1994
- Occurrence of Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitans in severe periodontitis in relation to age and treatment historyJournal of Clinical Periodontology, 1990
- Effect of modified Widman flap surgery and systemic tetracycline on the subgingival microbiota of periodontal lesionsJournal of Clinical Periodontology, 1988
- Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitans in human periodontal diseasesJournal of Clinical Periodontology, 1988
- The capability of Actinobacillus actinomycetemcomitans, Bacteroides gingivalis and Bacteroides intermedius to indicate progressive periodontitis; a retrospective studyJournal of Clinical Periodontology, 1987
- The occurrence of Actinobacillus actinomycetemcomitans, Bacteroides gingivalis and Bacteroides intermedius in destructive periodontal disease in adultsJournal of Clinical Periodontology, 1986
- Clinical and Microbiological Evaluation of Therapy for Juvenile PeriodontitisThe Journal of Periodontology, 1985
- Microbiological and clinical effects of surgical treatment of localized juvenile periodontitisJournal of Clinical Periodontology, 1985
- Suppression of the periodontopathic microflora in localized juvenile periodontitis by systemic tetracyclineJournal of Clinical Periodontology, 1983