Long‐term respiratory symptoms following oesophageal atresia
Open Access
- 6 April 2011
- journal article
- Published by Wiley in Acta Paediatrica
- Vol. 100 (9), 1222-1225
- https://doi.org/10.1111/j.1651-2227.2011.02279.x
Abstract
Oesophageal atresia (OA) is a congenital malformation that can lead to persistent respiratory symptoms in adulthood. To describe the prevalence of respiratory symptoms in adulthood in a population-based study of patients with repaired OA and to compare this with the prevalence in the general population. Of 80 patients operated for OA in Gothenburg in 1968–1983, 79 were located. The patients received a questionnaire on respiratory symptoms. Controls were 4979 gender- and age-matched subjects who answered the same questions. The questionnaire was answered by 73 of 79 (92%) patients. Physician-diagnosed asthma was reported by 30% in the OA group vs 10% in the control group (OR 4.1; 95% CI 2.4–6.8), and recurrent wheeze in 29% vs 5.5% (OR 6.9; 4.1–11.6). Also wheeze during the last year, asthma medication, a long-standing cough, cough with sputum production and chronic bronchitis were significantly more common among the patients with OA. In contrast, there was no significant difference regarding risk factors for asthma. The prevalence of respiratory symptoms did not appear to decrease with age. A high prevalence of respiratory symptoms remains among adult patients with repaired OA. Many of the patients had an asthma diagnosis. However, asthma heredity or allergic rhinitis was not overrepresented.Keywords
This publication has 19 references indexed in Scilit:
- Dysphagia in Adults Operated On for Esophageal Atresia - Use of a Symptom Score to Evaluate Correlated FactorsEuropean Journal of Pediatric Surgery, 2011
- Repaired oesophageal atresia: respiratory morbidity and pulmonary function in adultsEuropean Respiratory Journal, 2010
- Large scale questionnaire survey on respiratory health in Sweden: Effects of late- and non-responseRespiratory Medicine, 2009
- West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthmaRespiratory Research, 2009
- Longitudinal Follow-up of Bronchial Inflammation, Respiratory Symptoms, and Pulmonary Function in Adolescents after Repair of Esophageal Atresia with Tracheoesophageal FistulaThe Journal of Pediatrics, 2008
- Oesophageal atresia and tracheo-oesophageal fistulaArchives of Disease in Childhood: Fetal & Neonatal, 2006
- Respiratory morbidity after repair of oesophageal atresia and tracheo-oesophageal fistula.Archives of Disease in Childhood, 1993
- Management of esophageal atresia: Review of 16 years' experienceJournal of Pediatric Surgery, 1988
- LONG TERM PULMONARY CONSEQUENCES OF OESOPHAGEAL ATRESIA WITH TRACHEO‐OESOPHAGEAL FISTULAActa Paediatrica, 1982
- Lung function in children following repair of tracheoesophageal fistulaThe Journal of Pediatrics, 1979