Porokeratosis of Mibelli: Successful treatment with topical 5% imiquimod cream
- 12 November 2003
- journal article
- case report
- Published by Wiley in Australasian Journal of Dermatology
- Vol. 44 (4), 281-283
- https://doi.org/10.1046/j.1440-0960.2003.00010.x
Abstract
A 77-year-old woman with a large porokeratosis of Mibelli on the left shin was successfully treated with topical 5% imiquimod cream applied to the entire lesion once daily without occlusion three times a week. A strong inflammatory reaction was achieved in 6 weeks of treatment. The lesion had been present for approximately 6 years and prior treatments included curettage and electrocautery, cryotherapy and topical 5-fluorouracil under occlusion. At the end of treatment with topical 5% imiquimod cream, punch biopsy was negative for porokeratosis. The lesion healed without scarring. At 24-month follow up there had been no sign of clinical recurrence.Keywords
This publication has 19 references indexed in Scilit:
- Imiquimod 5% cream in the treatment of superficial basal cell carcinoma: Results of a multicenter 6-week dose-response trialJournal of the American Academy of Dermatology, 2001
- Imiquimod 5% cream in the treatment of Bowen's diseaseJournal of the American Academy of Dermatology, 2001
- Therapeutic response of basal cell carcinoma to the immune response modifier imiquimod 5% creamJournal of the American Academy of Dermatology, 1999
- Successful treatment of porokeratosis of Mibelli with diamond fraise dermabrasionArchives of Dermatology, 1992
- Porokeratosis and malignant skin tumorsZeitschrift für Krebsforschung und Klinische Onkologie, 1991
- Squamous Cell Carcinoma Arising in Porokeratosis of MibelliInternational Journal of Dermatology, 1986
- Linear porokeratosis: Treatment with the carbon dioxide laserJournal of the American Academy of Dermatology, 1986
- Porokeratosis (Mibelli): Treatment with topical 5-fluorouracilJournal of the American Academy of Dermatology, 1983
- Bowen disease associated with porokeratosis of MibelliArchives of Dermatology, 1975
- Fluorouracil ointment treatment of porokeratosis of MibelliArchives of Dermatology, 1973