Cell Contact-dependent Functional Selectivity of β2-Adrenergic Receptor Ligands in Stimulating cAMP Accumulation and Extracellular Signal-regulated Kinase Phosphorylation
Open Access
- 1 February 2012
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 287 (9), 6362-6374
- https://doi.org/10.1074/jbc.m111.301820
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- Divergent agonist selectivity in activating β1- and β2-adrenoceptors for G-protein and arrestin couplingBiochemical Journal, 2011
- Crystal structure of the β2 adrenergic receptor–Gs protein complexNature, 2011
- A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signalingProceedings of the National Academy of Sciences of the United States of America, 2007
- Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCRThe EMBO Journal, 2006
- Double transfection improves small interfering RNA‐induced thrombin receptor (PAR‐1) gene silencing in DU 145 prostate cancer cellsFEBS Letters, 2004
- Adhesion Regulation of Stromal Cell-derived Factor-1 Activation of ERK in Lymphocytes by PhosphatasesPublished by Elsevier BV ,2003
- Modelling of promiscuous receptor–Gi/Gs-protein coupling and effector responseTrends in Pharmacological Sciences, 2001
- Specificity and mechanism of action of some commonly used protein kinase inhibitorsBiochemical Journal, 2000
- Integrins Regulate the Linkage between Upstream and Downstream Events in G Protein-coupled Receptor Signaling to Mitogen-activated Protein KinasePublished by Elsevier BV ,2000
- Signaling Transduction Pathway of Angiotensin II in Human Mesangial Cells: Mediation of Focal Adhesion and GTPase Activating ProteinsBiochemical and Biophysical Research Communications, 1999