Electroencephalography in Mesial Temporal Lobe Epilepsy: A Review
Open Access
- 17 June 2012
- journal article
- review article
- Published by Hindawi Limited in Epilepsy Research and Treatment
- Vol. 2012, 1-17
- https://doi.org/10.1155/2012/637430
Abstract
Electroencephalography (EEG) has an important role in the diagnosis and classification of epilepsy. It can provide information for predicting the response to antiseizure drugs and to identify the surgically remediable epilepsies. In temporal lobe epilepsy (TLE) seizures could originate in the medial or lateral neocortical temporal region, and many of these patients are refractory to medical treatment. However, majority of patients have had excellent results after surgery and this often relies on the EEG and magnetic resonance imaging (MRI) data in presurgical evaluation. If the scalp EEG data is insufficient or discordant, invasive EEG recording with placement of intracranial electrodes could identify the seizure focus prior to surgery. This paper highlights the general information regarding the use of EEG in epilepsy, EEG patterns resembling epileptiform discharges, and the interictal, ictal and postictal findings in mesial temporal lobe epilepsy using scalp and intracranial recordings prior to surgery. The utility of the automated seizure detection and computerized mathematical models for increasing yield of non-invasive localization is discussed. This paper also describes the sensitivity, specificity, and predictive value of EEG for seizure recurrence after withdrawal of medications following seizure freedom with medical and surgical therapy.Keywords
This publication has 132 references indexed in Scilit:
- Strategies for adapting automated seizure detection algorithmsMedical Engineering & Physics, 2007
- Mesial Temporal Lobe Epilepsy with Hippocampal SclerosisEpilepsia, 2004
- Interictal Spike Detection Using the Walsh TransformIEEE Transactions on Biomedical Engineering, 2004
- Neocortical Temporal Lobe Epilepsy: Intracranial EEG Features and Surgical OutcomeJournal of Clinical Neurophysiology, 1999
- Familial temporal lobe epilepsy: A common disorder identified in twinsAnnals of Neurology, 1996
- Characteristics of medial temporal lobe epilepsy: I. Results of history and physical examinationAnnals of Neurology, 1993
- Withdrawal of Anticonvulsant Drugs in Patients Free of Seizures for Two YearsNew England Journal of Medicine, 1988
- Discontinuing Antiepileptic Medication in Children with Epilepsy after Two Years without SeizuresNew England Journal of Medicine, 1985
- ELECTROPHYSIOLOGICAL CORRELATES OF PATHOLOGY AND SURGICAL RESULTS IN TEMPORAL LOBE EPILEPSYBrain, 1975
- THE SURGICAL PROGNOSTIC SIGNIFICANCE OF THE ELECTROENCEPHALOGRAPHIC PREDICTION OF AMMON'S HORN SCLEROSIS IN EPILEPTICSJournal of Neurology, Neurosurgery & Psychiatry, 1958