SENSITIVITY OF A DOUBLE‐BLIND TRIAL OF RITODRINE AND PLACEBO IN TWIN PREGNANCY
- 1 May 1980
- journal article
- clinical trial
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 87 (5), 393-395
- https://doi.org/10.1111/j.1471-0528.1980.tb04566.x
Abstract
A critical examination is made of the results of a recently reported double blind trial comparing ritodrine and placebo. It is shown that interval estimates are more informative than p-values obtained from significance tests and that the trial involving 49 patients was insensitive to differences which could be clinically important. Contrary to the conclusions presented, the data suggest that further evaluation of the effects of ritodrine in twin pregnancies is necessary to clarify the situation.Keywords
This publication has 3 references indexed in Scilit:
- DOUBLE BLIND TRIAL OF RITODRINE AND PLACEBO IN TWIN PREGNANCYBJOG: An International Journal of Obstetrics and Gynaecology, 1979
- The two‐period cross‐over clinical trial.British Journal of Clinical Pharmacology, 1979