Different available varieties of Banana flowers, during their three crop seasons, were tested for hypoglycaemic effect on healthy, adult, normal rabbits. Chloroform soluble components of the January crop of variety „Ney poovan” showed maximum degree of hypoglycaemia. Chemical tests indicated presence of saponins, tannins, reducing and non–reducing sugars, reducing factors, sterols, glycosides, unsaturated compounds, waxes, fats and fatty acids. Sugars, saponifiable and the non–saponifiable matters were separated. Both saponifiable and non–saponifiable fractions produced hypoglycaemia. On separation of the components of unsaponifiable fraction through a column of alumina, five crystalline fractions were obtained. The third fraction, m.p. 129–31, existing in form of shining white needles, induced a maximum degree of hypoglycaemia of 18 to 21 mg in an oral dose of 10 mg/kg. General pharmacological investigations indicated this substance to be hypotensive on mongrel dogs and depressant on isolated heart of frog. The metabolic fate of this substance appeared to be in the biological system. Von den verschiedenen in Indien vorkommenden Formen von Musa sapientum zeigten die Blüten der von den Einheimischen als „Ney poovan” bezeichneten eine besonders starke hypoglykämische „Wirkung. Durch Trennung der unverseifbaren Fraktion über eine Aluminiumoxydsäule wurden 5 kristalline Komponenten erhalten, von denen sich eine als besonders stark wirksam erwies.