Survival after Treatment with Phenylacetate and Benzoate for Urea-Cycle Disorders
Open Access
- 31 May 2007
- journal article
- research article
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 356 (22), 2282-2292
- https://doi.org/10.1056/nejmoa066596
Abstract
The combination of intravenous sodium phenylacetate and sodium benzoate has been shown to lower plasma ammonium levels and improve survival in small cohorts of patients with historically lethal urea-cycle enzyme defects.Keywords
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