Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction
- 11 October 2016
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 134 (15), 1059-1067
- https://doi.org/10.1161/circulationaha.116.023142
Abstract
Background:Physical exertion, anger, and emotional upset are reported to trigger acute myocardial infarction (AMI). In the INTERHEART study, we explored the triggering association of acute physical activity and anger or emotional upset with AMI to quantify the importance of these potential triggers in a large, international population. Methods:INTERHEART was a case-control study of first AMI in 52 countries. In this analysis, we included only cases of AMI and used a case-crossover approach to estimate odds ratios for AMI occurring within 1 hour of triggers. Results:Of 12 461 cases of AMI 13.6% (n=1650) engaged in physical activity and 14.4% (n=1752) were angry or emotionally upset in the case period (1 hour before symptom onset). Physical activity in the case period was associated with increased odds of AMI (odds ratio, 2.31; 99% confidence interval [CI], 1.96–2.72) with a population-attributable risk of 7.7% (99% CI, 6.3–8.8). Anger or emotional upset in the case period was associated with an increased o...Keywords
This publication has 49 references indexed in Scilit:
- Emotional triggers in myocardial infarction: do they matter?European Heart Journal, 2012
- Physical, Psychological and Chemical Triggers of Acute Cardiovascular EventsCirculation, 2011
- Public health importance of triggers of myocardial infarction: a comparative risk assessmentThe Lancet, 2011
- Intensity of physical exertion and triggering of myocardial infarction: a case-crossover studyEuropean Heart Journal, 2008
- Meta-analysis of possible external triggers of acute myocardial infarctionInternational Journal of Cardiology, 2005
- Association of psychosocial risk factors with risk of acute myocardial infarction in 11 119 cases and 13 648 controls from 52 countries (the INTERHEART study): case-control studyThe Lancet, 2004
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control studyThe Lancet, 2004
- Global Burden of Cardiovascular DiseasesCirculation, 2001
- Anger report predicts coronary artery vasomotor response to mental stress in atherosclerotic segmentsThe American Journal of Cardiology, 1993
- PSYCHOLOGICAL STRESS AND FATAL HEART ATTACK: THE ATHENS (1981) EARTHQUAKE NATURAL EXPERIMENTThe Lancet, 1983