Biomechanical properties of the cornea measured by the Ocular Response Analyzer and their association with intraocular pressure and the central corneal curvature
- 1 November 2009
- journal article
- research article
- Published by Taylor & Francis Ltd in Clinical and Experimental Optometry
- Vol. 92 (6), 469-475
- https://doi.org/10.1111/j.1444-0938.2009.00414.x
Abstract
The aim of this study was to investigate the biomechanical properties of the cornea and their association with intraocular pressure (IOP), central corneal thickness (CCT) and the central corneal radius of curvature (Rc).Eighty-three eyes were divided into two groups. The biomechanical properties of the cornea were measured in 63 normal eyes and in 20 post-laser in situ keratomileusis (LASIK) eyes. The IOP, corneal hysteresis (CH) and corneal resistance factor (CRF) were measured by the Ocular Response Analyzer (ORA). The Rc and CCT were measured using the corneal topographer Medmont E-300 and the Tomey SP-100 Handy ultrasonic pachymeter. Other parameters measured by the ORA, such as TimeIn and TimeOut, were also studied.A mean corneal hysteresis of 10.8 mmHg and CRF of 10.6 mmHg were recorded for the normal eyes. There was no significant association with central curvature. All parameters measured by the ORA showed a significant correlation with the CCT, except for the corneal-compensated intraocular pressure (IOPcc). Both IOPs measured by the ORA had the same values for the mean CH and CRF. For the post-LASIK eyes, the CH and CRF were lower than in the normal non-operated eyes. The TimeIn and the TimeOut also presented lower values for the post-LASIK eyes, suggesting that additional data can be obtained with the ORA measurements.The results of this study indicate that there is no correlation between the parameters measured with the Ocular Response Analyzer and central corneal radius of curvature. Some of the biomechanical properties of the cornea studied were found to differ in the normal eyes compared to the post-LASIK eyes.Keywords
This publication has 17 references indexed in Scilit:
- Pilot Study on the Influence of Corneal Biomechanical Properties Over the Short Term in Response to Corneal Refractive Therapy for MyopiaCornea, 2008
- Correlations between corneal hysteresis, intraocular pressure, and corneal central pachymetryJournal of Cataract & Refractive Surgery, 2008
- Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyesJournal of Cataract & Refractive Surgery, 2007
- Assessment of the Biomechanical Properties of the Cornea with the Ocular Response Analyzer in Normal and Keratoconic EyesInvestigative Ophthalmology & Visual Science, 2007
- Changes in Corneal Biomechanics and Intraocular Pressure Following LASIK Using Static, Dynamic, and Noncontact TonometryAmerican Journal of Ophthalmology, 2007
- Central Corneal Thickness and Corneal Hysteresis Associated With Glaucoma DamageAmerican Journal of Ophthalmology, 2006
- Finite element analysis applied to cornea reshapingJournal of Biomedical Optics, 2005
- Determining in vivo biomechanical properties of the cornea with an ocular response analyzerJournal of Cataract & Refractive Surgery, 2005
- Interferometric technique to measure biomechanical changes in the cornea induced by refractive surgeryJournal of Cataract & Refractive Surgery, 2005
- Influence of corneal biomechanical properties on intraocular pressure measurementJournal of Cataract & Refractive Surgery, 2005