Cu(II)-Mediated Methylthiolation of Aryl C−H Bonds with DMSO
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- 11 March 2010
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 12 (7), 1644-1647
- https://doi.org/10.1021/ol100449c
Abstract
An unprecedented Cu(II)-mediated methylthiolation of aryl C−H bonds under oxidative conditions that employs the widely available DMSO as the methylthiolation reagent is described. Various functional groups in the substrates were tolerated, and ethylthiolation was also successfully achieved directly from diethyl sulfoxide under the same reaction conditions.Keywords
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