Impact of Antidepressant Drug Adherence on Comorbid Medication Use and Resource Utilization

Abstract

Depression affects 32.6 million to 35.1 million adults in the United States each year and has a lifetime prevalence of 16.2%, but it still often goes undiagnosed, with documented gaps in the quality of care provided by primary care and other nonpsychiatric practitioners.^1,2 As a result, the economic burden of depression is high, estimated to be $81.5 billion annually, fueled primarily by losses in work productivity and high relapse rates.³