Pulmonary arterial hypertension preceding idiopathic pulmonary fibrosis in a BMPR2 mutation positive patient
Open Access
- 28 February 2014
- journal article
- Published by European Respiratory Society (ERS) in European Respiratory Review
- Vol. 23 (131), 147-149
- https://doi.org/10.1183/09059180.00005513
Abstract
Asthma commonly occurs in pregnant females, and recent data have outlined the risks of adverse perinatal outcomes among this population. There is an increased risk of low birth weight and small for gestational age, particularly among females with moderate-to-severe asthma and exacerbations during pregnancy. There is also an increased risk of preterm birth, especially with oral steroid use, a small but statistically significant increased risk of congenital malformations, particularly of cleft lip with or without cleft palate, and an increased risk of neonatal hospitalisation and death. Active management may reduce these risks, possibly through reductions in exacerbations.This publication has 9 references indexed in Scilit:
- Managing diagnostic procedures in idiopathic pulmonary fibrosisEuropean Respiratory Review, 2013
- Gremlin Plays a Key Role in the Pathogenesis of Pulmonary HypertensionCirculation, 2012
- Idiopathic pulmonary fibrosis: guidelines for diagnosis and clinical management have advanced from consensus-based in 2000 to evidence-based in 2011European Respiratory Journal, 2011
- Role of Gremlin in the LungAmerican Journal of Respiratory Cell and Molecular Biology, 2010
- ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association Developed in Collaboration With the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension AssociationJournal of the American College of Cardiology, 2009
- Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertensionAmerican Journal of Physiology-Lung Cellular and Molecular Physiology, 2008
- Gremlin-mediated Decrease in Bone Morphogenetic Protein Signaling Promotes Pulmonary FibrosisAmerican Journal of Respiratory and Critical Care Medicine, 2008
- Gremlin localization and expression levels partially differentiate idiopathic interstitial pneumonia severity and subtypeThe Journal of Pathology, 2007
- Bone Morphogenetic Protein-4 Inhibitor Gremlin Is Overexpressed in Idiopathic Pulmonary FibrosisThe American Journal of Pathology, 2006