Effects of enriched environments with different durations and starting times on learning capacity during aging in rats assessed by a refined procedure of the Hebb‐Williams maze task
Open Access
- 18 October 2002
- journal article
- research article
- Published by Wiley in Journal of Neuroscience Research
- Vol. 70 (3), 340-346
- https://doi.org/10.1002/jnr.10442
Abstract
Cognitive function as measured by the Hebb-Williams maze task was examined in Fischer 344 male rats that had been exposed to an enriched environment for periods of variable duration and at different starting ages. In one experiment, rats were exposed to environmental enrichment from weaning until the age of 2.5, 15, or 25 months. The results of 12 problems of the Hebb-Williams maze task showed that the enriched rearing condition improved the learning ability in all the age groups; however, factor analysis and ANOVA demonstrated that four of the 12 maze problems were not suitable for detecting the effect of age under different environmental conditions. Reanalysis of the results obtained with the other eight maze problems more clearly revealed both the effects of rearing condition and aging. The latter analysis demonstrated that the learning rate of rats reared under enriched conditions was faster than that of rats reared under standard social conditions. Short-term (3-month) exposure also had positive effects on cognitive function in both adult (11-month-old) and aged (22-month-old) animals. The effect of long-term exposure to an enriched environment starting at weaning was much greater than that of short-term exposure in aged rats, whereas the effects of both long-term and short-term exposure were almost the same in adult rats. These results show that aged animals still have appreciable plasticity in cognitive function, and suggest that environmental stimulation could benefit aging humans as well.Keywords
This publication has 35 references indexed in Scilit:
- Decreased synaptic density in aged brains and its prevention by rearing under enriched environment as revealed by synaptophysin contentsJournal of Neuroscience Research, 1994
- Brief exposure to an enriched environment improves performance on the Morris water task and increases hippocampal cytosolic protein kinase C activity in young ratsBehavioural Brain Research, 1992
- Effect of housing in an enriched environment on the size of the cerebral cortex in young and old ratsExperimental Neurology, 1987
- Spatial memory and visual evoked potentials in young and old rats after housing in an enriched environmentBehavioral and Neural Biology, 1985
- Facilitative effects of maternal environmental enrichment on maze learning in rat offspringPhysiology & Behavior, 1985
- Differential rearing effects on rat visual cortex synapses. I. Synaptic and neuronal density and synapses per neuronBrain Research, 1985
- Rat Brain: Effects of Environmental Enrichment on Wet and Dry WeightsScience, 1969
- Early experience and problem-solving ability.Journal of Comparative and Physiological Psychology, 1968
- Effects of environmental complexity and training on brain chemistry.Journal of Comparative and Physiological Psychology, 1960
- The effects of experimental variations on problem solving in the rat.Journal of Comparative and Physiological Psychology, 1952