Acral myxoinflammatory fibroblastic sarcoma in FNAB samples: can we distinguish it from other myxoid lesions?
- 24 April 2003
- journal article
- Published by Wiley in Cytopathology
- Vol. 14 (2), 73-78
- https://doi.org/10.1046/j.1365-2303.2003.00020.x
Abstract
We analysed cytomorphological characteristics of three fine needle aspiration biopsy (FNAB) samples of acral myxoinflammatory fibroblastic sarcoma (AMIFS) as well as the features of a number of other benign and malignant myxoid lesions. The analysis showed that FNAB samples from two cases of AMIFS had similar cytomorphology, containing all the characteristic features described in surgical biopsies: myxoid material, spindle cells with bipolar cytoplasmic extensions, epithelioid cells with globules of extra-cellular material, ganglion-like and lipoblast-like giant cells. Only the inflammatory component was scarce. The third sample did not contain features typical of AMIFS. Samples from other myxoid tumours resembled AMIFS to some extent, however, none of them contained all three tumour components characteristic of AMIFS. Cytomorphology of AMIFS may be characteristic enough to enable a definitive diagnosis from FNAB, provided all the distinctive features are sampled.Keywords
This publication has 12 references indexed in Scilit:
- Distinct cytologic features of spindle cell lipomaCancer, 2001
- Cytoarchitectural findings in the diagnosis of primary soft tissue tumors.Acta Cytologica, 2001
- The value of fine-needle aspiration biopsy in the differential diagnosis of adult myxoid sarcomaCancer, 2000
- Myxofibrosarcoma of soft tissues: Cytomorphologic analysis of a seriesDiagnostic Cytopathology, 1999
- Inflammatory Myxoid Tumor of the Soft Parts with Bizarre Giant CellsPathology - Research and Practice, 1998
- Acral Myxoinflammatory Fibroblastic SarcomaThe American Journal of Surgical Pathology, 1998
- Benign fibrous lesions masquerading as sarcomasActa Orthopaedica, 1997
- Fine-needle aspiration cytopathology of soft tissue: Chondromyxoid and myxoid lesionsDiagnostic Cytopathology, 1995
- Low grade fibromyxoid sarcoma: clinicopathological analysis of eleven new cases in support of a distinct entityHistopathology, 1995
- Extraskeletal myxoid chondrosarcoma: Fine‐needle aspiration biopsy findingsDiagnostic Cytopathology, 1994