Vitreomacular traction and exudative age‐related macular degeneration
- 22 July 2008
- journal article
- review article
- Published by Wiley in Acta Ophthalmologica
- Vol. 86 (5), 470-481
- https://doi.org/10.1111/j.1755-3768.2008.01210.x
Abstract
Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation have already begun by the time tractional forces lead to a change for the worse. Vitreomacular traction alone is perhaps not able to induce AMD. It would seem sensible to consider vitreous changes when diagnosing and treating AMD patients because of the high coincidence of vitreomacular traction and choroidal neovascularization (CNV) and the often successful treatment of other diseases of the vitreoretinal interface by vitrectomy. The concept of the pathogenesis of AMD should therefore be extended to include the influence of the vitreous, especially where therapeutic concepts such as pharmacological vitreolysis and vitreous separation have been established as causative treatment of late forms of AMD.Keywords
This publication has 96 references indexed in Scilit:
- Age-related Macular Degeneration and the Immune Response: Implications for TherapyAmerican Journal of Ophthalmology, 2007
- Guidance for the treatment of neovascular age-related macular degenerationActa Ophthalmologica Scandinavica, 2007
- Age-related macular degeneration: a perspective on genetic studiesEye, 2007
- Current Treatment Approaches in Diabetic Macular EdemaOphthalmologica, 2007
- High incidence of vitreomacular traction in recurrent choroidal neovascularisation after repeated photodynamic therapyBritish Journal of Ophthalmology, 2006
- AUTOLOGOUS PLASMIN FOR PHARMACOLOGIC VITREOLYSIS PREPARED 1 HOUR BEFORE SURGERYRetina, 2006
- New therapies for neovascular age-related macular degeneration: critical appraisal of the current evidenceActa Ophthalmologica Scandinavica, 2006
- Posterior vitreous detachment and macular hole formation in myopic foveoschisisAmerican Journal of Ophthalmology, 2004
- Treatment of pigment epithelial detachments due to age-related macular degeneration with intra-ocular C3F8 injection*Australian and New Zealand Journal of Ophthalmology, 1998
- Evolution of soft drusen in age-related macular degenerationEye, 1994