Moderate alcoholic beverage intake and early nuclear and cortical lens opacities
- 1 January 2004
- journal article
- Published by Swets & Zeitlinger Publishers in Ophthalmic Epidemiology
- Vol. 11 (1), 53-65
- https://doi.org/10.1076/opep.11.1.53.26439
Abstract
To study the relationship between alcoholic beverage intake and early lens opacities. 556 Boston-area women aged 53-74 years were sampled from the Nurses' Health Study cohort. Degree of opacity was assessed by eye examinations including lens photography. After multivariate adjustment, the odds of a nuclear opacity grade > or =2.3 increased by 30% (OR=1.3, 95% CI: 1.10-1.54) per 10-g increase in total alcohol intake. Furthermore, after control for intake of other alcoholic beverages, the odds of a higher nuclear opacity grade increased by 13% (OR=1.13, 95% CI: 1.02-1.26) for every two additional hard-alcoholic drinks consumed per week, and by 17% (OR=1.17, 95% CI: 1.03-1.33) for every two additional glasses of wine consumed per week. The odds of a cortical opacity grade > or =0.4 decreased by 12% (OR=0.88, 95% CI: 0.79-0.98) for every two additional glasses of wine consumed per week, but intake of other alcoholic beverages was unrelated to cortical opacity. Consumption of alcoholic beverages, particularly hard liquor and wine, was positively related to nuclear opacity. Wine drinking was inversely related to cortical opacity.Keywords
This publication has 14 references indexed in Scilit:
- Identification and in Vitro Biological Activities of Hop Proanthocyanidins: Inhibition of nNOS Activity and Scavenging of Reactive Nitrogen SpeciesJournal of Agricultural and Food Chemistry, 2002
- Wine PhenolicsAnnals of the New York Academy of Sciences, 2002
- Alcohol and eye diseases: a review of epidemiologic studies.Journal of Studies on Alcohol, 2001
- Wine and Your HeartCirculation, 2001
- Risk Factors for Cortical, Nuclear, and Posterior Subcapsular Cataracts: The POLA StudyAmerican Journal of Epidemiology, 2000
- Antioxidant Intake and Risk of Incident Age-related Nuclear Cataracts In the Beaver Dam Eye StudyAmerican Journal of Epidemiology, 1999
- Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits?BMJ, 1996
- Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wineThe Lancet, 1993
- Alcohol Use and Risk of Posterior Subcapsular OpacitiesAmerican Journal of Ophthalmology, 1993
- Drugs, including alcohol, that act as risk factors for cataract, and possible protection against cataract by aspirin-like analgesics and cyclopenthiazide.British Journal of Ophthalmology, 1988