Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
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Open Access
- 1 April 2012
- journal article
- research article
- Published by American Association for Cancer Research (AACR) in Cancer Research
- Vol. 72 (7), 1773-1783
- https://doi.org/10.1158/0008-5472.can-11-3831
Abstract
This important study has immediate clinical implications because it suggests ways that autophagy inhibitors such as chloroquine might be combined with antiangiogenic therapies to limit a mechanism of resistance and thereby extend efficacy.Keywords
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