Genetic Relatedness of Recently Collected Spanish Respiratory Tract Streptococcus pneumoniae Isolates with Reduced Susceptibility to Amoxicillin

Abstract

Of Streptococcus pneumoniae isolates from 17 hospitals, 9.8% were amoxicillin nonsusceptible (MIC ≥ 4 μg/ml). The genetic relatedness of 138 isolates was studied by pulsed-field gel electrophoresis. Although 44 different clones were detected, more than 62% of these isolates were related to four clones (Spain ^23F -1, Spain ^6B -2, Spain ^9V -3, and Spain ¹⁴ -5).