Is there a genetic basis for Fuchs' heterochromic uveitis? Discordance in monozygotic twins.
Open Access
- 1 January 1992
- journal article
- case report
- Published by BMJ in British Journal of Ophthalmology
- Vol. 76 (1), 22-24
- https://doi.org/10.1136/bjo.76.1.22
Abstract
One pair, and probably two pairs, of monozygotic twins are reported with discordance for Fuchs' heterochromic uveitis (FHU). Regular Mendelian inheritance of this disease is now proved to be impossible. The heritability of FHU is low and may be zero. The possibility of any genetic predisposition to the disease and its association with 'simple' heterochromia are discussed.Keywords
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