Poly(ADP-ribose) polymerase inhibition protects epileptic hippocampal neurons from apoptosis via suppressing Akt-mediated apoptosis-inducing factor translocation in vitro
- 29 November 2012
- journal article
- Published by Elsevier BV in Neuroscience
- Vol. 231, 353-362
- https://doi.org/10.1016/j.neuroscience.2012.11.009
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (81071041, 81100971, 81000557)
This publication has 41 references indexed in Scilit:
- Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic toleranceEuropean Journal of Neuroscience, 2012
- Imidazoquinolinone, Imidazopyridine, and Isoquinolindione Derivatives as Novel and Potent Inhibitors of the Poly(ADP-ribose) Polymerase (PARP): A Comparison with Standard PARP InhibitorsMolecular Pharmacology, 2008
- Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticusExperimental Neurology, 2007
- Apoptosis signalling pathways in seizure-induced neuronal death and epilepsyBiochemical Society Transactions, 2007
- Endocannabinoids block status epilepticus in cultured hippocampal neuronsEuropean Journal of Pharmacology, 2007
- Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and Status EpilepticusThe Journal of pharmacology and experimental therapeutics, 2006
- Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly(ADP-ribose) polymerase-1Cardiovascular Research, 2004
- Poly(ADP-ribose) Polymerase-1-mediated Cell Death in Astrocytes Requires NAD+ Depletion and Mitochondrial Permeability TransitionJournal of Biological Chemistry, 2004
- Poly(ADP‐ribose) polymerase‐1 activity promotes NF‐κB‐driven transcription and microglial activation: implication for neurodegenerative disordersJournal of Neurochemistry, 2003
- Effect of Poly(ADP-Ribose) Polymerase Inhibitors on the Ischemia-Reperfusion-Induced Oxidative Cell Damage and Mitochondrial Metabolism in Langendorff Heart Perfusion SystemMolecular Pharmacology, 2001