THE treatment of chromophobe pituitary tumor or its complications consists in roentgen irradiation, surgery or a combination of the two, and the administration of natural or synthetic hormonal substances when secondary glandular deficiencies exist. In the majority of instances the primary object of treatment is the arrest or restoration of visual loss; evaluation of treatment, therefore, is based largely on its effect on this function. In general it has been thought that the secondary constitutional effects were inconstant and relatively unimportant in comparison to the danger of loss of vision, especially since little could be done to correct these effects. The restoring of vision is obviously of the greatest importance; but to achieve the best result the patient should also have relief of other symptoms, an increase in well being and an ability to return to work. The combined efforts of the neurosurgeon, radiologist and internist may be necessary to achieve this end.