Risk of New Vertebral Fracture in the Year Following a Fracture

Abstract

Vertebral fractures are a well-recognized consequence of postmenopausal bone loss and are the most common osteoporotic fractures.¹ It is estimated that less than one third of all vertebral fractures are clinically diagnosed.² However, all vertebral fractures, whether symptomatic or radiographically identified, are associated with increased mortality and morbidity, including back pain and decreased activity, with consequent increased days of bed rest.^3-5 Vertebral fractures are associated with increased risk of further vertebral fractures, with resulting height loss and kyphosis, as well as increased risk of nonvertebral fractures.^6-10 This increased risk remains after correction for bone mineral density (BMD), itself a potent risk factor for fracture.^6,10,11