Angular measurements of light scattered by turbid chiral media using linear Stokes polarimeter
- 1 January 2006
- journal article
- research article
- Published by SPIE-Intl Soc Optical Eng in Journal of Biomedical Optics
- Vol. 11 (4), 041105-041105-10
- https://doi.org/10.1117/1.2339134
Abstract
The effects of turbid chiral media on light polarization are studied in different directions around the scattering samples using a refined linear Stokes polarimeter, which simplifies the signal analysis, and allows for the detailed investigations of scattered light. Because no moving parts are involved in a measurement at a specific detection direction, the determination accuracy of polarization states is increased. The results show that light depolarization increases with both turbidity and detection angle for low and moderately turbid samples; however, the angular dependence decreases with increasing turbidity. When the turbidity is increased to , the depolarization becomes higher in the forward than in the backward direction. Polarization sensitive Monte Carlo simulations are used to verify some experimental observations. The results also demonstrate that surviving linear polarization fraction and overall intensity are more sensitive to the increase of glucose concentration in backward than in the forward direction in highly turbid media, indicating that backward geometry may be preferable for potential glucose detection in a biomedical context. Comparison measurements with optically inactive glycerol suggest that the refractive index matching effect, and not the chiral nature of the solute, dominates the observed optical rotation engendered by glucose in highly turbid media.
Keywords
This publication has 28 references indexed in Scilit:
- New optical scheme for a polarimetric-based glucose sensorJournal of Biomedical Optics, 2004
- Balanced detection for low-noise precision polarimetric measurements of optically active, multiply scattering tissue phantomsJournal of Biomedical Optics, 2004
- Noninvasive Blood Glucose Monitoring With Optical Coherence TomographyDiabetes Care, 2002
- Keeping watch on glucoseIEEE Spectrum, 2002
- Developing Efficient, High-Capacity Metropolitan Area Networks (OPN Trends Supplement)Optics and Photonics News, 2001
- Optical glucose sensing in biological fluids: an overviewJournal of Biomedical Optics, 2000
- Effect of molecular concentrations in tissu-simulating phantoms on images obtained using diffuse reflectance polarimetry.Optics Express, 1998
- Correlation between blood glucose concentration in diabetics and noninvasively measured tissue optical scattering coefficientOptics Letters, 1997
- Influence of glucose concentration on light scattering in tissue-simulating phantomsOptics Letters, 1994
- Possible correlation between blood glucose concentration and the reduced scattering coefficient of tissues in the near infraredOptics Letters, 1994