Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective
Top Cited Papers
- 13 September 2009
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Nanotechnology
- Vol. 4 (10), 634-641
- https://doi.org/10.1038/nnano.2009.242
Abstract
The regulation of engineered nanoparticles requires a widely agreed definition of such particles. Nanoparticles are routinely defined as particles with sizes between about 1 and 100 nm that show properties that are not found in bulk samples of the same material. Here we argue that evidence for novel size-dependent properties alone, rather than particle size, should be the primary criterion In any definition of nanoparticles when making decisions about their regulation for environmental, health and safety reasons. We review the size-dependent properties of a variety of inorganic nanoparticles and find that particles larger than about 30 nm do not in general show properties that would require regulatory scrutiny beyond that required for their bulk counterparts.Keywords
This publication has 99 references indexed in Scilit:
- Effect of nanoparticle size on the onset temperature of surface meltingMaterials Letters, 2009
- Entrapment of Hydrophobic Drugs in Nanoparticle Monolayers with Efficient Release into Cancer CellsJournal of the American Chemical Society, 2009
- Religious beliefs and public attitudes toward nanotechnology in Europe and the United StatesNature Nanotechnology, 2008
- Unique Cellular Interaction of Silver Nanoparticles: Size-Dependent Generation of Reactive Oxygen SpeciesThe Journal of Physical Chemistry B, 2008
- Nanomaterials at work in biomedical researchNature Materials, 2008
- The effect of particle design on cellular internalization pathwaysProceedings of the National Academy of Sciences of the United States of America, 2008
- The melting behavior of aluminum nanoparticlesThermochimica Acta, 2007
- Size tailoring of TiO2 anatase nanoparticles in aqueous medium and synthesis of nanocomposites. Characterization by Raman spectroscopyJournal of Materials Chemistry, 2003
- Surface heterogeneity of mineralsComptes Rendus Geoscience, 2002
- Size dependence of the ferroelectric transition of smallparticles: Effect of depolarizationPhysical Review B, 1994