Prevention of Acute Kidney Injury in Children Undergoing Cardiac Surgery: A Narrative Review
- 8 January 2018
- journal article
- review article
- Published by SAGE Publications in World Journal for Pediatric and Congenital Heart Surgery
- Vol. 9 (1), 79-90
- https://doi.org/10.1177/2150135117743211
Abstract
Children undergoing cardiac surgery are at risk of developing acute kidney injury (AKI). Preventing cardiac surgery–associated AKI (CS-AKI) is important as it is associated with increased early- and long-term mortality and morbidity. Targeting modifiable risk factors (eg, avoiding poor renal perfusion, nephrotoxic drugs, and fluid overload) reduces the risk of CS-AKI. There is currently no strong evidence for the routine use of pharmacological approaches (eg, aminophylline, dexmedetomidine, fenoldopam, and steroids) to prevent CS-AKI. There is robust evidence to support the role of early peritoneal dialysis as a nonpharmacologic approach to prevent CS-AKI.Keywords
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