Specificity of the bacteriophage PBS2-induced inhibitor of uracil-DNA glycosylase
- 13 October 1981
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 20 (21), 6092-6096
- https://doi.org/10.1021/bi00524a027
Abstract
The purified phage PBS2-coded inhibitor of uracil-DNA glycosylase (Ura-DNA glycosylase) from Bacillus subtilis was tested for its ability to inhibit this enzyme isolated from other prokaryotic and from eukaryotic sources. The inhibitor was also assayed for its effect on DNA glycosylases specific for other base residues in DNA. Ura-DNA glycosylases from a variety of sources are equally sensitive to inhibition by the inhibitor. DNA glycosylases specific for base residues in DNA other than uracil are not inhibited by the PBS2-coded inhibitor.This publication has 19 references indexed in Scilit:
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