Cumulative incidence of chronic constipation: a population‐based study 1988–2003
Open Access
- 6 October 2007
- journal article
- Published by Wiley in Alimentary Pharmacology & Therapeutics
- Vol. 26 (11-12), 1521-1528
- https://doi.org/10.1111/j.1365-2036.2007.03540.x
Abstract
Aim To estimate the cumulative incidence of chronic constipation and evaluate potential risk factors. Methods In previous cross‐sectional studies in 1988, random samples of Olmsted County, MN residents were mailed valid gastrointestinal symptoms surveys. A similar survey was mailed in 2003 to all the remaining eligible subjects who had been mailed to previously. An incident case of chronic constipation was defined as no reported constipation or irritable bowel syndrome on their initial survey but reported constipation on the second survey. Results In all, 5507 (79%) subjects responded to the initial survey and 2298 (55%) subjects responded to the second survey in which chronic constipation could be defined. Over 12 years, the cumulative incidence of chronic constipation was 17.4% (14.5, 20.5). Among those less than age 50 years at baseline, the incidence of chronic constipation differed by gender (9.2% in men vs. 18.3% in women). In those over 70 years, the incidence of chronic constipation was more similar for men and women (20.6% vs. 25.0%). The other risk factor associated with new onset chronic constipation was the presence of abdominal pain at baseline [OR = 2.0 (1.3, 3.0)]. Conclusion The cumulative incidence of chronic constipation over more than a decade was almost one in six, and more pronounced in women and the elderly.Keywords
This publication has 34 references indexed in Scilit:
- Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in postmenopausal womenNeurogastroenterology & Motility, 2006
- The Health-Related Quality of Life and Economic Burden of ConstipationPharmacoEconomics, 2005
- A community-based, controlled study of the epidemiology and pathophysiology of dyspepsiaClinical Gastroenterology and Hepatology, 2004
- The Threat to Medical-Records ResearchThe New England Journal of Medicine, 1997
- Chronic constipation—Is the work-up worth the cost?Diseases of the Colon & Rectum, 1997
- History of the Rochester Epidemiology ProjectMayo Clinic Proceedings, 1996
- U. S. Householder survey of functional gastrointestinal disordersDigestive Diseases and Sciences, 1993
- Demographic and dietary determinants of constipation in the US population.American Journal of Public Health, 1990
- Bowel function and transit rate during the menstrual cycle.Gut, 1989
- SOME PRELIMINARY FINDINGS ON PHYSICAL COMPLAINTS FROM A PROSPECTIVE STUDY OF 1,064,004 MEN AND WOMENAmerican Journal of Public Health and the Nations Health, 1964