Desmopressin Response of Enuretic Children
- 1 October 1983
- journal article
- research article
- Published by American Medical Association (AMA) in American Journal of Diseases of Children
- Vol. 137 (10), 962-963
- https://doi.org/10.1001/archpedi.1983.02140360026009
Abstract
• To characterize the children with enuresis likely to respond to desmopressin acetate, we performed a double-blind crossover study that included the use of a placebo. During the two weeks of desmopressin administration, six children (12%) had 13 or 14 dry nights, and 15 children (29%) had eight to 12 dry nights. Among the 17 children aged 9 years or older, with four to seven dry nights during the two-week baseline period, 12 children (71%) responded to desmopressin (eight to 14 dry nights). In contrast, none of the 15 children younger than 9 years of age with fewer than three dry nights before therapy responded. During the posttreatment period, only four of the 21 drug responders reported a persistent effect. Desmopressin may be effective in reducing the frequency of enuresis, especially in children older than 9 years of age without nightly enuresis. (Am J Dis Child1983;137:962-963)This publication has 3 references indexed in Scilit:
- Desmopressin in the Management of Nocturnal Enuresis in Children: A Double-Blind StudyPediatrics, 1978
- DDAVP IN CHILDHOOD NOCTURNAL ENURESISActa Paediatrica, 1978
- DESMOPRESSIN AS A TREATMENT FOR ENURESISThe Lancet, 1977