Penetration of Rifampin through Staphylococcus epidermidis Biofilms
Open Access
- 1 March 2002
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 46 (3), 900-903
- https://doi.org/10.1128/aac.46.3.900-903.2002
Abstract
Rifampin penetrated biofilms formed by Staphylococcus epidermidis but failed to effectively kill the bacteria. Penetration was demonstrated by a simple diffusion cell bioassay and by transmission electron microscopic observation of antibiotic-affected cells at the distal edge of the biofilm.Keywords
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