Annexin A1: Novel roles in skeletal muscle biology
- 23 April 2012
- journal article
- review article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 227 (8), 3007-3015
- https://doi.org/10.1002/jcp.24032
Abstract
Annexin A1 (ANXA1, lipocortin‐1) is the first characterized member of the annexin superfamily of proteins, so called since their main property is to bind (i.e., to annex) to cellular membranes in a Ca2+‐dependent manner. ANXA1 has been involved in a broad range of molecular and cellular processes, including anti‐inflammatory signalling, kinase activities in signal transduction, maintenance of cytoskeleton and extracellular matrix integrity, tissue growth, apoptosis, and differentiation. New insights show that endogenous ANXA1 positively modulates myoblast cell differentiation by promoting migration of satellite cells and, consequently, skeletal muscle differentiation. This suggests that ANXA1 may contribute to the regeneration of skeletal muscle tissue and may have therapeutic implications with respect to the development of ANXA1 mimetics. J. Cell. Physiol. 227: 3007–3015, 2012.Keywords
This publication has 82 references indexed in Scilit:
- Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscleBMC Genomics, 2011
- Regulation of Vascular Endothelial Growth Factor-induced Endothelial Cell Migration by LIM Kinase 1-mediated Phosphorylation of Annexin 1Published by Elsevier BV ,2010
- Exploiting the Annexin A1 pathway for the development of novel anti‐inflammatory therapeuticsBritish Journal of Pharmacology, 2009
- 3D Timelapse Analysis of Muscle Satellite Cell MotilityThe International Journal of Cell Cloning, 2009
- International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) FamilyPharmacological Reviews, 2009
- Annexin‐A1: a pivotal regulator of the innate and adaptive immune systemsBritish Journal of Pharmacology, 2008
- Myoblast Fusion in Fly and Vertebrates: New Genes, New Processes and New PerspectivesTraffic, 2008
- Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cellsThe EMBO Journal, 2007
- Post‐translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surfaceThe FASEB Journal, 2006
- Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor‐dependent, transcription‐independent mechanismBritish Journal of Pharmacology, 2000