Complementary Effects of Pravastatin and Nicotinic Acid in the Treatment of Combined Hyperlipidaemia in Diabetic and Non-Diabetic Patients

Abstract

Background: Given that treatment with a single drug is frequently unsuccessful in patients with combined hyperlipidaemia, there is a rationale for the study of regimens using drugs that have complementary therapeutic profiles. We therefore set out to compare the efficacy of a combined pravastatin and nicotinic acid regimen with higher dose monotherapy using either drug in patients with non-insulin-dependent diabetes and in non-diabetic patients with combined hyperlipidaemia.