Mortality Resulting From Congenital Heart Disease Among Children and Adults in the United States, 1999 to 2006
Top Cited Papers
- 30 November 2010
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 122 (22), 2254-2263
- https://doi.org/10.1161/circulationaha.110.947002
Abstract
Background—: Previous reports suggest that mortality resulting from congenital heart disease (CHD) among infants and young children has been decreasing. There is little population-based information on CHD mortality trends and patterns among older children and adults. Methods and Results—: We used data from death certificates filed in the United States from 1999 to 2006 to calculate annual CHD mortality by age at death, race-ethnicity, and sex. To calculate mortality rates for individuals ≥1 year of age, population counts from the US Census were used in the denominator; for infant mortality, live birth counts were used. From 1999 to 2006, there were 41 494 CHD-related deaths and 27 960 deaths resulting from CHD (age-standardized mortality rates, 1.78 and 1.20 per 100 000, respectively). During this period, mortality resulting from CHD declined 24.1% overall. Mortality resulting from CHD significantly declined among all race-ethnicities studied. However, disparities persisted; overall and among infants, mortality resulting from CHD was consistently higher among non-Hispanic blacks compared with non-Hispanic whites. Infant mortality accounted for 48.1% of all mortality resulting from CHD; among those who survived the first year of life, 76.1% of deaths occurred during adulthood (≥18 years of age). Conclusions—: CHD mortality continued to decline among both children and adults; however, differences between race-ethnicities persisted. A large proportion of CHD-related mortality occurred during infancy, although significant CHD mortality occurred during adulthood, indicating the need for adult CHD specialty management.Keywords
This publication has 46 references indexed in Scilit:
- Children and Adults With Congenital Heart Disease Lost to Follow-UpCell Metabolism, 2009
- Including prenatal diagnoses in birth defects monitoring: Experience of the Metropolitan Atlanta Congenital Defects ProgramBirth Defects Research Part A: Clinical and Molecular Teratology, 2008
- Descriptive epidemiology of congenital heart disease in Northern EnglandPaediatric and Perinatal Epidemiology, 2008
- Transition of care from paediatric to adult services in cardiologyArchives of Disease in Childhood, 2007
- Racial differences in infant mortality attributable to birth defects in the United States, 1989–2002Birth Defects Research Part A: Clinical and Molecular Teratology, 2006
- The influence of prenatal diagnosis on postnatal outcome in patients with structural congenital heart diseasePrenatal Diagnosis, 2004
- Prenatal diagnosis, pregnancy terminations and prevalence of Down syndrome in AtlantaBirth Defects Research Part A: Clinical and Molecular Teratology, 2004
- First‐year survival of infants born with congenital heart defects in Arkansas (1993‐1998): A survival analysis using registry dataBirth Defects Research Part A: Clinical and Molecular Teratology, 2003
- An overview of infant mortality and birth defects in the United StatesTeratology, 1997
- Epidemiology of congenital heart disease in the United StatesAmerican Heart Journal, 1994