Metformin and Incident Breast Cancer among Diabetic Women: A Population-Based Case–Control Study in Denmark
Open Access
- 1 January 2011
- journal article
- Published by American Association for Cancer Research (AACR) in Cancer Epidemiology, Biomarkers & Prevention
- Vol. 20 (1), 101-111
- https://doi.org/10.1158/1055-9965.epi-10-0817
Abstract
Background: Preliminary evidence suggests that metformin may decrease breast cancer risk by decreasing insulin levels and reducing cell proliferation. We evaluated the effect of metformin medication on the risk of incident breast cancer among peri- and postmenopausal women.Keywords
This publication has 24 references indexed in Scilit:
- Metformin and Other Biguanides in Oncology: Advancing the Research AgendaCancer Prevention Research, 2010
- Long-Term Metformin Use Is Associated With Decreased Risk of Breast CancerDiabetes Care, 2010
- Combined randomised controlled trial experience of malignancies in studies using insulin glargineDiabetologia, 2009
- New Users of Metformin Are at Low Risk of Incident CancerDiabetes Care, 2009
- Insulin-Like Growth Factor Type 1 Receptor and Insulin Receptor Isoform Expression and Signaling in Mammary Epithelial CellsEndocrinology, 2009
- Long-term All-Cause Mortality in Cancer Patients With Preexisting Diabetes MellitusJAMA, 2008
- High insulin levels in newly diagnosed breast cancer patients reflect underlying insulin resistance and are associated with components of the insulin resistance syndromeBreast Cancer Research and Treatment, 2008
- Insulin in the Adjuvant Breast Cancer Setting: A Novel Therapeutic Target for Lifestyle and Pharmacologic Interventions?Journal of Clinical Oncology, 2008
- Insulin-like growth factors and neoplasiaNature Reviews Cancer, 2004
- Validity of breast cancer in the Danish Cancer Registry. A study based on clinical records from one county in DenmarkEuropean Journal Of Cancer Prevention, 2002