Molecular, Functional, and Pathological Aspects of the Mitochondrial ADP/ATP Carrier
- 1 August 2006
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 21 (4), 242-249
- https://doi.org/10.1152/physiol.00005.2006
Abstract
In providing the cell with ATP generated by oxidative phosphorylation, the mitochondrial ADP/ATP carrier plays a central role in aerobic eukaryotic cells. Combining biochemical, genetic, and structural approaches contributes to understanding the molecular mechanism of this essential transport system, the dysfunction of which is implicated in neuromuscular diseases.Keywords
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