L-Tryptophan in Mania
- 1 January 1974
- journal article
- clinical trial
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 30 (1), 56-62
- https://doi.org/10.1001/archpsyc.1974.01760070040006
Abstract
Five manic patients were treated with chlorpromazine hydrochloride (CPZ), then with L-tryptophan (LTP), and five with LTP first, then CPZ, in a double-blind, placebo-controlled crossover study. LTP was slightly superior to CPZ in all regards. Mania and depression may be linked by a central indoleamine deficit.Keywords
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