Adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin
Open Access
- 1 January 2009
- journal article
- research article
- Published by Springer Science and Business Media LLC in Critical Care
- Vol. 13 (4), R112
- https://doi.org/10.1186/cc7956
Abstract
Critically ill patients requiring intensive care uniformly develop insulin resistance. This is most pronounced in patients with sepsis. Recently, several hormones secreted by adipose tissue have been identified to be involved in overall insulin sensitivity in metabolic syndrome-related conditions. However, little is known about these adipokines in critical illness.This publication has 29 references indexed in Scilit:
- Glucose Metabolism and Insulin Resistance in SepsisCurrent Pharmaceutical Design, 2008
- Effect of Intensive Insulin Therapy on Insulin Sensitivity in the Critically IllJournal of Clinical Endocrinology & Metabolism, 2007
- Adiponectin Sensitizes Insulin Signaling by Reducing p70 S6 Kinase-mediated Serine Phosphorylation of IRS-1Journal of Biological Chemistry, 2007
- Retinol-Binding Protein 4 and Insulin Resistance in Lean, Obese, and Diabetic SubjectsThe New England Journal of Medicine, 2006
- Adiponectin: a key adipocytokine in metabolic syndromeClinical Science, 2006
- Intensive Insulin Therapy in the Medical ICUThe New England Journal of Medicine, 2006
- Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetesNature, 2005
- Plasma Leptin Levels in Trauma Patients: Effect of Adjuvant Recombinant Human Growth Hormone in Intravenously Fed Multiple Trauma PatientsJournal of Parenteral and Enteral Nutrition, 1998
- Acute and Chronic Effect of Insulin on Leptin Production in Humans: Studies In Vivo and In VitroDiabetes, 1996
- Changes in the serum concentrations of thyroxine-binding prealbumin and retinol-binding protein following burn injuryClinica Chimica Acta; International Journal of Clinical Chemistry, 1982