Prosthesis-patient mismatch: definition, clinical impact, and prevention
Top Cited Papers
- 1 August 2006
- Vol. 92 (8), 1022-1029
- https://doi.org/10.1136/hrt.2005.067363
Abstract
Prosthesis-patient mismatch (PPM) is present when the effective orifice area of the inserted prosthetic valve is too small in relation to body size. Its main haemodynamic consequence is to generate higher than expected gradients through normally functioning prosthetic valves. This review updates the present knowledge about the impact of PPM on clinical outcomes. PPM is common (20–70% of aortic valve replacements) and has been shown to be associated with worse haemodynamic function, less regression of left ventricular hypertrophy, more cardiac events, and lower survival. Moreover, as opposed to most other risk factors, PPM can largely be prevented by using a prospective strategy at the time of operation.Keywords
This publication has 47 references indexed in Scilit:
- Hemodynamic Performance and Incidence of Patient-Prosthesis Mismatch of the Complete Supraannular Perimount Magna Bioprosthesis in the Aortic PositionThe Thoracic and Cardiovascular Surgeon, 2005
- Impact of Prosthesis–Patient Size on Functional Recovery After Aortic Valve ReplacementCirculation, 2005
- Hemodynamic Comparison of Bioprostheses for Complete Supra-Annular Position in Patients With Small Aortic AnnulusJournal of the American College of Cardiology, 2005
- Impact of valve prosthesis-patient mismatch on pulmonary arterial pressure after mitral valve replacementJournal of the American College of Cardiology, 2005
- Why Angina in Aortic Stenosis With Normal Coronary Arteriograms?Circulation, 2003
- Functional Changes in Coronary Microcirculation After Valve Replacement in Patients With Aortic StenosisCirculation, 2003
- Left ventricular architecture after valve replacement due to critical aortic stenosis: an approach to dis-/qualify the myth of valve prosthesis–patient mismatch?☆European Journal of Cardio-Thoracic Surgery, 2001
- Validation and applications of mitral prosthetic valvular areas calculated by Doppler echocardiographyThe American Journal of Cardiology, 1990
- Decreased Coronary ReserveNew England Journal of Medicine, 1982
- The problem of valve prosthesis-patient mismatch.Circulation, 1978