A Quinoline Antibiotic from Rhodococcus erythropolis JCM 6824
- 1 November 2008
- journal article
- research article
- Published by Springer Science and Business Media LLC in The Journal of Antibiotics
- Vol. 61 (11), 680-682
- https://doi.org/10.1038/ja.2008.96
Abstract
A new quinoline antibiotic, aurachin RE, was isolated and identified from a culture broth of Rhodococcus erythropolis JCM 6824. The aurachin RE structure was determined based on NMR and mass spectrometric analysis. The structure is similar to that of aurachin C antibiotics that have been identified from Stigmatella aurantiaca. Compared to aurachin C, however, aurachin RE exhibits a wide and strong antimicrobial spectrum against both high- and low-GC Gram-positive bacteria.Keywords
This publication has 8 references indexed in Scilit:
- Three Types of Antibiotics Produced from Rhodococcus erythropolis StrainsMicrobes and Environments, 2008
- Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171The Journal of Antibiotics, 2007
- A Type II Polyketide Synthase from the Gram‐Negative Bacterium Stigmatella aurantiaca Is Involved in Aurachin Alkaloid BiosynthesisAngewandte Chemie-International Edition, 2007
- Lariatins, Antimycobacterial Peptides Produced by Rhodococcus sp. K01−B0171, Have a Lasso StructureJournal of the American Chemical Society, 2006
- Novel 2,4-Dichlorophenoxyacetic Acid Degradation Genes from Oligotrophic Bradyrhizobium sp. Strain HW13 Isolated from a Pristine EnvironmentJournal of Bacteriology, 2002
- Characterization of the Ubiquinol Oxidation Sites in Cytochromes bo and bd from Escherichia coli using Aurachin C AnaloguesThe Journal of Biochemistry, 1999
- Rhodopeptins (Mer-N1033), Novel Cyclic Tetrapeptides with Antifungal Activity from Rhodococcus sp. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities.The Journal of Antibiotics, 1999
- The aurachins, new quinoline antibiotics from myxobacteria : Production, physico-chemical and biological properties.The Journal of Antibiotics, 1987