Autism: The Phenotype in Relatives
- 1 January 1998
- journal article
- review article
- Published by Springer Science and Business Media LLC in Journal of Autism and Developmental Disorders
- Vol. 28 (5), 369-392
- https://doi.org/10.1023/a:1026048320785
Abstract
There is broad agreement that genetic influences are central in the development of idiopathic autism. Whether relatives manifest genetically related milder phenotypes, and if so how these relate to autism proper, has proved a more contentious issue. A review of the relevant studies indicates that relatives are sometimes affected by difficulties that appear conceptually related to autistic behaviors. These range in severity from pervasive developmental disorders to abnormalities in only one area of functioning, and possibly extend to related personality traits. Issues involved in clarifying the components of milder phenotypes and their relationship to autism are outlined.Keywords
This publication has 78 references indexed in Scilit:
- Autism in Down's syndrome: family history correlatesJournal of Intellectual Disability Research, 1997
- Parents and collateral relatives of children with pervasive developmental disorders: A family history studyAmerican Journal of Medical Genetics, 1995
- Can standard measures identify subclinical markers of autism?Journal of Autism and Developmental Disorders, 1993
- Clinical and genetic relationships between autism‐pervasive developmental disorder and Tourette syndrome: A study of 19 casesAmerican Journal of Medical Genetics, 1991
- Does the autistic child have a “theory of mind” ?Cognition, 1985
- AN ISLET OF ABILITY IN AUTISTIC CHILDREN: A RESEARCH NOTEJournal of Child Psychology and Psychiatry, 1983
- Influence of extraversion and neuroticism on subjective well-being: Happy and unhappy people.Journal of Personality and Social Psychology, 1980
- A Comparative Study of Infantile Autism and Specific Developmental Receptive Language DisorderThe British Journal of Psychiatry, 1975
- IV. Parental Personality and Attitude and Childhood PsychosesThe British Journal of Psychiatry, 1971
- A Five- to Fifteen-Year Follow-up Study of Infantile PsychosisThe British Journal of Psychiatry, 1969