The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake
Open Access
- 20 September 2009
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Medicine
- Vol. 15 (10), 1195-1201
- https://doi.org/10.1038/nm.2026
Abstract
No abstract availableKeywords
This publication has 55 references indexed in Scilit:
- Lifestyle and Pharmacological Approaches to Weight Loss: Efficacy and SafetyJournal of Clinical Endocrinology & Metabolism, 2008
- SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in MiceCell Metabolism, 2008
- Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficitsHippocampus, 2008
- Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanismsNature Medicine, 2008
- A Foxo/Notch pathway controls myogenic differentiation and fiber type specificationJCI Insight, 2007
- FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell HomeostasisCell, 2007
- Central insulin action in energy and glucose homeostasisJCI Insight, 2006
- Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesityJCI Insight, 2006
- Missense polymorphism in the human carboxypeptidase E gene alters enzymatic activityHuman Mutation, 2001
- Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activityNature Genetics, 1995