Nationwide Study of Escherichia coli and Klebsiella pneumoniae Producing Extended-Spectrum β-Lactamases in Spain
Open Access
- 1 May 2005
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (5), 2122-2125
- https://doi.org/10.1128/aac.49.5.2122-2125.2005
Abstract
Clonal dissemination of extended-spectrum β-lactamases (ESBL) in 170 Escherichia coli isolates and 70 Klebsiella pneumoniae isolates from a nationwide study of 40 Spanish centers in 2000 was not observed in most centers. The most prevalent ESBL were CTX-M-9 (27.3%), SHV-12 (23.9%), and CTX-M-14 (20.5%) for E. coli and TEM-3 (16.7%) and TEM-4 (25%) for K. pneumoniae . A new ESBL, TEM-133, with mutations L21F, E104K, and R164S, was identified.Keywords
This publication has 17 references indexed in Scilit:
- Identification and Broad Dissemination of the CTX-M-14 β-Lactamase in Different Escherichia coli Strains in the Northwest Area of SpainJournal of Clinical Microbiology, 2002
- Epidemiology of Extended-Spectrum β-Lactamase-Producing Enterobacter Isolates in a Spanish Hospital during a 12-Year PeriodJournal of Clinical Microbiology, 2002
- Prevalence of extended spectrum β-lactamase (ESBL)-producing clinical isolates in the Asia-Pacific region and South Africa: regional results from SENTRY Antimicrobial Surveillance Program (1998–99)Diagnostic Microbiology and Infectious Disease, 2002
- Genes Encoding TEM-4, SHV-2, and CTX-M-10 Extended-Spectrum β-Lactamases Are Carried by MultipleKlebsiella pneumoniaeClones in a Single Hospital (Madrid, 1989 to 2000)Antimicrobial Agents and Chemotherapy, 2002
- Occurrence of Extended-Spectrum β-Lactamases in Members of the Family Enterobacteriaceae in Italy: Implications for Resistance to β-Lactams and Other Antimicrobial DrugsAntimicrobial Agents and Chemotherapy, 2002
- Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance ThreatClinical Microbiology Reviews, 2001
- Outer membrane protein change combined with co-existing TEM-1 and SHV-1 beta-lactamases lead to false identification of ESBL-producing Klebsiella pneumoniaeJournal of Antimicrobial Chemotherapy, 2001
- Cloning and Sequence of the Gene Encoding a Novel Cefotaxime-Hydrolyzing β-Lactamase (CTX-M-9) from Escherichia coli in SpainAntimicrobial Agents and Chemotherapy, 2000
- Epidemiology of Ciprofloxacin Resistance and Its Relationship to Extended-Spectrum -Lactamase Production in Klebsiella pneumoniae Isolates Causing BacteremiaClinical Infectious Diseases, 2000
- Outbreak of a Multiresistant Klebsiella pneumoniae Strain in an Intensive Care Unit: Antibiotic Use as Risk Factor for Colonization and InfectionClinical Infectious Diseases, 2000